Shona Mookerjee, PhD

Associate Professor, College of Osteopathic Medicine, Basic Sciences

Areas of Expertise

Mitochondrial Biology and Bioenergetics


  • Ph.D., Molecular Genetics, University of Rochester, Rochester, NY, 2006
  • B.A., Biology and Envt. Sci., Carleton College, Northfield, MN

Recent Publications

Selected publications:

  1. 2021 Mookerjee, S.A., Gerencser, A.A., Watson, M.A, Brand, M.D. Controlled power: how biology manages succinate-driven energy release. Biochemical Society Transactions, 49(6):2929-2939. doi: 10.1042/BST20211032.
  2. 2021 Labbé, K., Mookerjee, S.A., Gibbs, E., Lerner, C.A., Nunnari, J. The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis. Journal of Cell Biology 220: e202103122, jcb.202103122
  3. 2020 Louie, M.C., Ton, J., Brady, M.L., Le., D.T., Mar, J.M., Lerner, C.A., Gerencser, A.A., Mookerjee, S.A. Total Cellular ATP Production Changes With Primary Substrate in MCF7 Breast Cancer Cells. Frontiers in Oncology 10:1703 doi:10.3389/fonc.2020.01703
  4. 2019 Handel, M.E., Brand, M.D., Mookerjee, S.A., The Whys and Hows of Calculating Total Cellular ATP Production Rate. Trends in Endocrinology and Metabolism 30: 412-416 doi: 10.1016/j.tem.2019.04.007.
  5. 2018 Mookerjee, S.A., Quinlan, C. L., Wong, H., Dighe, P, Brand, M.D. Plate-based measurements of respiration by isolated mitochondria Methods in Molecular Biology 1782: 301-313. doi 10.1007/978-1-4939-7831-1_17
  6. 2018 Gunter, A., Gerencser, A.A., Phuong, L., Bornstein, S., Mookerjee, S.A., Maridas, D., Brand, M.D., Rosen, C. Metabolic Programming of Mesenchymal Progenitor Cells Characterize Lineage Allocation. Journal of Bone and Mineral Research 33(6):1052-1065. doi: 10.1002/jbmr.3390
  7. 2017 Gerencser, A.A*, Mookerjee, S.A*., Jastroch, M., Brand, M.D. Positive Feedback Amplifies the Response of Mitochondrial Membrane Potential to Glucose Concentration in Clonal Pancreatic Beta Cells. Biochimica et Biophysica Acta 1863(5): 1054-1065 (doi: 10.1016/j.bbadis.2016.10.015. published online 2016 Oct 20)

*These authors contributed equally

  1. 2017 Mookerjee, S.A., Gerencser, A.A., Nicholls, D.G., Brand, M.D. Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements. Journal of Biological Chemistry 292(17): 7189-7207