Faculty & Staff at TUC
Karl Meszaros
College: COP
Department: Biological & Pharmaceutical Sciences
Title: Professor
Phone: (707) 638-5244
Fax: (707) 638-5959
E-Mail: kmeszaro@touro.edu
Office: Administration & Faculty 2, Rm. 204
Institution | Degree | Field of Study | Obtained |
Semmelweis University, Budapest | M.D. | Medicine | 1971 |
Semmelweis University, Budapest | Ph.D | Biology | 1978 |
Biology, Pathophysiology
Carbohydrate and fat metabolism
Obesity
Diabetes
Education
1. Mészáros K, Antoni F, Hrabák A, Szikla C, Garzó T, Tompa A, Lapis K. Prevention
of the hepatotoxic effects of D-galactosamine by D-galactose. FEBS Lett. 1973;35(1):1-3.
2. Mészáros K, Antoni F, Mandl J, Hrabák A, Garzó T. Effects of D-galactosamine on
nucleotide metabolism and microsomal membranes in mouse liver. FEBS Lett. 1974;44(2):141-5.
3. Mészáros K, Mandl J, Antoni F, Garzó T. Inhibition of protein synthesis by hexosamine
containing glycogen formed in mouse liver after treatment with D-galactosamine. FEBS
Lett. 1976;71(2):215-9.
4. Tompa A, Lapis K, Schaff Z, Mészáros K, Mandl J, Garzó T, Antoni F. Cytoplasmic
aggregates in D-galactosamine induced liver injury. Acta Morphol Acad Sci Hung. 1977;25(4):239-57.
5. Mandl J, Garzó T, Mészáros K, Antoni F. Epinephrine and glucagon counteract inhibition
of protein synthesis induced by D-galactosamine in isolated mouse hepatocytes. Biochim
Biophys Acta. 1979;586(3):560-7.
6. Mészáros K, Chance B, Holtzer H. Myoglobin and cytochrome oxidase in the myocardium
of the developing chick. J Mol Cell Cardiol. 1980;12(10):965-75.
7. Tihanyi K, Mészáros K, Horváth I. Inhibition of microsomal drug metabolism by mitochondria
and cytochrome c oxidation of extramitochondrial NADPH. Biochem Pharmacol. 1982;31(5):661-3.
8. Mandl J, Mészáros K, Antoni F, Spolarics Z, Garzó T. Reversible inhibition of RNA
synthesis and irreversible inhibition of protein synthesis by D-galactosamine in isolated
mouse hepatocytes. Mol Cell Biochem. 1982;46(1):25-30.
9. Puskás M, Antoni F, Péterfy F, Mészáros K. Pokeweed mitogen, Bordetella pertussis
and breast milk cell factor induce preferentially the synthesis of different immunoglobulin
classes. Boll Ist Sieroter Milan. 1983;62(3):262-7.
10. Krasznai A, Arányi P, Fehér T, Krajcsi P, Mészáros K, Horváth I. Alterations in
the number of glucocorticoid receptors of circulating lymphocytes in sepsis. Haematologia
(Budapest). 1986;19(4):293-8.
11. Krasznai A, Krajcsi P, Arányi P, Mészáros K, Horváth I. Decreased number of steroid
receptors of circulating lymphocytes in Crohn'sdisease and ulcerative colitis. Haematologia
(Budapest). 1986;19(4):299-301.
12. Mészáros K, Bagby GJ, Lang CH, Spitzer JJ. Increased uptake and phosphorylation
of 2-deoxyglucose by skeletal muscles in endotoxin-treated rats. Am J Physiol. 1987;253(1
Pt 1):E33-9.
13. Mészáros K, Lang CH, Bagby GJ, Spitzer JJ. Contribution of different organs to
increased glucose consumption after endotoxin administration. J Biol Chem. 1987;262(23):10965-70.
14. Mészáros K, Lang CH, Bagby GJ, Spitzer JJ. Tumor necrosis factor increases in
vivo glucose utilization of macrophage-rich tissues. Biochem Biophys Res Commun. 1987;149(1):1-6.
15. Spitzer JJ, Bagby GJ, Mészáros K, Lang CH. Alterations in lipid and carbohydrate
metabolism in sepsis. JPEN J Parenter Enteral Nutr. 1988;12(6 Suppl):53S-58S.
16. Mészáros K, Lang CH, Bagby GJ, Spitzer JJ. In vivo glucose utilization by individual
tissues during nonlethal hypermetabolic sepsis. FASEB J. 1988;2(15):3083-6.
17. Spitzer JJ, Bagby GJ, Meszaros K, Lang CH. Altered control of carbohydrate metabolism
in endotoxemia. Prog Clin Biol Res. 1989;286:145-65.
18. Spitzer JJ, Bagby GJ, Hargrove DM, Lang CH, Mészáros K. Alterations in the metabolic
control of carbohydrates in sepsis. Prog Clin Biol Res. 1989;308:545-61.
19. Mészáros K, Lang CH, Bojta J, Spitzer JJ. Early changes in glucose utilization
of individual tissues after endotoxin administration. Circ Shock. 1989;29(2):107-14.
20. Mészáros K, Lang CH, Hargrove DM, Spitzer JJ. Tissue glucose utilization during
epinephrine-induced hyperglycemia. J Appl Physiol. 1989;67(5):1770-5.
21. de Boisblanc BP, Meszaros K, Cairo J, Spitzer JJ, Summer W. Diaphragmatic fatigue
after endotoxemic shock in rats: in vitro function and metabolism. J Med. 1990;21(1-2):7-26.
22. Bautista AP, Mészáros K, Bojta J, Spitzer JJ. Superoxide anion generation in the
liver during the early stage of endotoxemia in rats. J Leukoc Biol. 1990;48(2):123-8.
23. Lang CH, Dobrescu C, Mészáros K. Insulin-mediated glucose uptake by individual
tissues duringsepsis. Metabolism. 1990; 39(10):1096-107.
24. Mészáros K, Bojta J, Bautista AP, Lang CH, Spitzer JJ. Glucose utilization by
Kupffer cells, endothelial cells, and granulocytes in endotoxemic rat liver. Am J
Physiol. 1991;260(1 Pt 1):G7-12.
25. Spolarics Z, Schuler A, Bagby GJ, Lang CH, Mészáros K, Spitzer JJ. Tumor necrosis
factor increases in vivo glucose uptake in hepatic nonparenchymal cells. J Leukoc
Biol. 1991;49(3): 309-12.
26. Mészáros K. Magnetic field elicits hypotension mediated by platelet activating
factor in rats injected with iron beads. Biochem Biophys Res Commun. 1991;180(1):315-22.
27. deBoisblanc BP, Meszaros K, Burns A, Bagby GJ, Nelson S, Summer WR. Effect of
dichloroacetate on mechanical performance and metabolism of compromised diaphragm
muscle. J Appl Physiol. 1992;72(3):1149-55.
28. Mészáros K, Parent JB, Gazzano-Santoro H, Little R, Horwitz A, Parsons T, Theofan
G, Grinna L, Weickmann J, Elsbach P, et al. A recombinant amino terminal fragment
of bactericidal/permeability-increasing protein inhibits the induction of leukocyte
responses by LPS. J Leukoc Biol. 1993;54(6):558-63.
29. Elsbach P, Weiss J, Doerfler M, Shu C, Kohn F, Ammons WS, Kung AH, Meszaros K,
Parent JB. The bactericidal/permeability increasing protein of neutrophils is a potent
antibacterial and anti-endotoxin agent in vitro and in vivo. Prog Clin Biol Res. 1994;388:41-51.
30. Theofan G, Horwitz AH, Williams RE, Liu PS, Chan I, Birr C, Carroll SF, Mészáros
K, Parent JB, Kasler H, et al. An amino-terminal fragment of human lipopolysaccharide-binding
protein retains lipid A binding but not CD14-stimulatory activity. J Immunol. 1994;152(7):3623-9.
31. Gazzano-Santoro H, Mészáros K, Birr C, Carroll SF, Theofan G, Horwitz AH, Lim
E, Aberle S, Kasler H, Parent JB. Competition between rBPI23, a recombinant fragment
of bactericidal/permeability-increasing protein, and lipopolysaccharide (LPS)-binding
protein for binding to LPS and gram-negative bacteria. Infect Immun. 1994;62(4):1185-91.
32. Mészáros K, Aberle S, Dedrick R, Machovich R, Horwitz A, Birr C, Theofan G, Parent
JB. Monocyte tissue factor induction by lipopolysaccharide (LPS): dependence on LPS-binding
protein and CD14, and inhibition by a recombinant fragment of bactericidal/permeability-increasing
protein. Blood. 1994;83(9):2516-25.
33. Mészáros K, Aberle S, White M, Parent JB. Immunoreactivity and bioactivity of
lipopolysaccharide-binding protein in normal and heat-inactivated sera. Infect Immun.
1995;63(1):363-5.
34. Luo J, Chuang T, Cheung J, Quan J, Tsai J, Sullivan C, Hector RF, Reed MJ, Meszaros
K, King SR, Carlson TJ, Reaven GM. Masoprocol (nordihydroguaiaretic acid): a new antihyperglycemic
agent isolated from the creosote bush (Larrea tridentata). Eur J Pharmacol. 1998;346(1):77-9.
35. Reed MJ, Meszaros K, Entes LJ, Claypool MD, Pinkett JG, Brignetti D, Luo J, Khandwala
A, Reaven GM. Effect of masoprocol on carbohydrate and lipid metabolism in a rat model
of Type II diabetes. Diabetologia. 1999;42(1):1026.
36. Reed MJ, Meszaros K, Entes LJ, Claypool MD, Pinkett JG, Gadbois TM, Reaven GM.
A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat. Metabolism.
2000;49(11):1390-4.
37. Antoni F., and K. Mészáros. Immunopeptides, peptide antigens. In: Biomedical Significance
of Peptide Research. Eds. F. Laszlo and F. Antoni. Publishing House of the Hungarian
Academy of Sciences, Budapest, p. 115-125, 1984.
38. Spitzer, J. J., G. J. Bagby, D. M. Hargrove, C. H. Lang, and K. Mészáros. Alterations
in the metabolic control of carbohydrates in sepsis. In: Progress in Clinical Biological
Research. Eds. E. Schlag and H. Redl. A. R. Liss, New York, 308: 545-561, 1989.
39. Spitzer, J. J., J. Bojta, C. H. Lang, and K. Mészáros. Cellular metabolic responses
in endotoxemia and a hypothesis for the mechanism of hepatic failure in endotoxin
shock. In: Shock, Trauma, Sepsis and Organ Failure. Eds G. Schlag, H. Reidl, J. H.
Siegel. Springer Verlag, New York. p. 278-303, 1990.
40. Spitzer, J. J., K. Mészáros, A. Bautista, C. H. Lang, and Z. Spolarics. Potential
contribution of phagocytic cells to liver damage after E. coli endotoxin. In: Cellular
and Molecular Aspects of Endotoxin Reactions. Vol. 1. Eds A. Novotny, J. J. Spitzer,
and E. J. Siegler. Elsevier, New York, p. 521-528, 1990.
41. Spitzer, J. J., Z. Spolarics, A. P. Bautista, K. Mészáros, A. Schuler, and C.
H. Lang. Increased glucose uptake and superoxide anion production after priming or
activation of hepatic phagocytes: a potential source of liver damage. In: Shock, Trauma,
Sepsis and Organ Failure. Eds G. Schlag, H Reidl, J. H. Siegel, and D. L. Traber.
Springer Verlag, New York. p. 235-249, 1991.
42. Conlon, P. J., H. Gazzano-Santoro, K. Mészáros, R. Little, K. Huang, J. Watkins,
S. Aberle, H. Kasler, D. Fishwild, G. Theofan, A, Horwitz and J. B. Parent. rBPI23:
A potent bactericidal and anti-endotoxin agent. In: Mediators of Sepsis. Eds J.-D.
Baumgartner, T. Calandra, J. Carlet. Medicine-Sciences Flammarion, Paris. p. 23-35,
1993.
43. Elsbach, P., J. Weiss, M. Doerfler, C. Shu, F. Kohn, W. S. Ammons, A. H. C. Kung,
K. Mészáros, J. B. Parent, H. Gazzano-Santoro, K. Huang, and D. Fishwild. The bactericidal/permeability
increasing protein of neutrophils is a potent antibacterial and anti-endotoxin agent
in vitro and in vivo. In: Bacterial Endotoxins. Basic Science to Anti-Sepsis Strategies.
Eds Levin, J., van Deventer, S. J .H., van der Poll, T., and Sturk, A. Wiley-Liss,
New York, p. 41-51, 1994.
44. Mészáros, K., K. Huang, H. Gazzano-Santoro, R. Dedrick, and J. B. Parent. Inhibition
of the effects of LPS on endothelial cells by rBPI21 Cys, a recombinant fragment of
bactericidal/permeability increasing protein. In: Immune consequences of Trauma, Sepsis
and Endotoxicosis. Ed. Faist, J. Springer, Berlin, Heidelberg, New York, p. 146-154,
1996.
45. Mészáros, K., M. Barnett, H. Wehring, D. Evans, D. Sasaki-Hill, P. Goldsmith,
and K. Knapp. Progress examination for assessing students’ readiness for advanced
pharmacy practice experiences. Am J of Pharm Educ, Vol 73, Issue 6, Article 109, 2009
46. Mészáros K, Lopes IC, Goldsmith PC, Knapp KK. Interprofessional education: cooperation among osteopathic medicine, pharmacy, and physician assistant students to recognize medical errors. J Am Osteopath Assoc. 2011 Apr;111(4):213-8. PubMed PMID: 21562289.
47. Meszaros, K., Barnett, M. J., Lenth, R. V., & Knapp, K. K. (2013). Pharmacy school survey standards revisited. Am J Pharm Educ, 77(1), 3. doi: 10.5688/ajpe7713
48.Alternative Viewpoint: Preparation for Residency. Katherine K. Knapp, Károly Mészáros, Paul C. Goldsmith, Gordon C. McCarter, Elizabeth Kelly Hester, et al. Pharmacotherapy 2014; 34(8):e157–e158; doi: 10.1002/phar.1475
Employer | Title | From - To |
Touro University - California | Associate Professor, then Professor | 1999 - present |
XOMA Corporation, Berkeley, CA | Senior Scientist | 1991 |
Louisiana State University, Department of Physiology, New Orleans | Assistant Professor | 1985 |
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